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Type 1 diabetes, DKA and HHS

A practice question in the style of the MCCQE MCQ exam. Choose your answer to see the explanation.

A 44-year-old man with type 2 diabetes is admitted with DKA. He takes empagliflozin, and his glucose was 13 mmol/L on arrival. After his DKA resolves, what should happen to empagliflozin?

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The answer is B: Stop it and review restarting.

SGLT2 inhibitors can trigger DKA, especially with low insulin reserve, illness or low carbohydrate intake. After DKA, the drug is stopped, and restarting it should be reconsidered carefully, often avoided, particularly if insulin deficiency is suspected.

This question comes from Week 4 of MCC Vault: Endocrine, diabetes and metabolic. That week has 124 more exam-style questions like it, 5 short lessons and 155 flashcards. The course starts free with Week 1 and reaches this topic in week 4, as part of a five-month plan with full mock exams along the way.

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