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Type 1 diabetes, DKA and HHS
A practice question in the style of the MCCQE MCQ exam. Choose your answer to see the explanation.
A 44-year-old man with type 2 diabetes is admitted with DKA. He takes empagliflozin, and his glucose was 13 mmol/L on arrival. After his DKA resolves, what should happen to empagliflozin?
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The answer is B: Stop it and review restarting.
SGLT2 inhibitors can trigger DKA, especially with low insulin reserve, illness or low carbohydrate intake. After DKA, the drug is stopped, and restarting it should be reconsidered carefully, often avoided, particularly if insulin deficiency is suspected.
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