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COPD

A practice question in the style of the MCCQE MCQ exam. Choose your answer to see the explanation.

A 74-year-old man with COPD (FEV1 38% predicted, four exacerbations last year, on home oxygen) has purulent sputum and increased breathlessness. Which antibiotic is most appropriate?

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The answer is B: Amoxicillin-clavulanate.

FEV1 below 50%, frequent exacerbations and home oxygen make this a complicated exacerbation, which calls for amoxicillin-clavulanate or a respiratory fluoroquinolone to cover resistant organisms. Amoxicillin, doxycycline and trimethoprim-sulfamethoxazole are for simple exacerbations. Nitrofurantoin is a urinary antibiotic.

This question comes from Week 2 of MCC Vault: Respiratory. That week has 124 more exam-style questions like it, 5 short lessons and 154 flashcards. The course starts free with Week 1 and reaches this topic in week 2, as part of a five-month plan with full mock exams along the way.

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