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Anemia and transfusion

A practice question in the style of the MCCQE MCQ exam. Choose your answer to see the explanation.

A woman who had a transfusion 8 days ago has a falling hemoglobin and jaundice. What is the most likely diagnosis?

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The answer is C: Delayed hemolytic reaction.

Delayed hemolytic reactions occur days to weeks after transfusion as antibodies to minor red cell antigens rise. The direct antiglobulin test is often positive.

This question comes from Week 5 of MCC Vault: Kidneys, fluids and blood. That week has 124 more exam-style questions like it, 5 short lessons and 150 flashcards. The course starts free with Week 1 and reaches this topic in week 5, as part of a five-month plan with full mock exams along the way.

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